Supernatural Vitale Elixir Refill

£75 30 mls

Relaxes wrinkles

Instant filling

Plumps & firms

This revolutionary cosmeceutical-grade facial muscle relaxant is proven through 3D in vitro testing to inhibit the muscle contractions responsible for fine lines and wrinkles by...

This revolutionary cosmeceutical-grade facial muscle relaxant is proven through 3D in vitro testing to inhibit the muscle contractions responsible for fine lines and wrinkles by up to 91% after 24 hours, while helping to provide an instant filling effect and rebuild the underlying skin structure for long term wrinkle resistance.

Harnessing a proprietary Neuropeptide Relaxant Complex that helps inhibit the skin’s intrinsic behaviour to tense, this targeted treatment delivers a new era of efficacy in wrinkle reduction and prevention, providing a natural, topical alternative to anti-wrinkle injections.

Instant Hydrafilling technology is delivered through Saccharide Isomerate and an innovative new degradation-resistant Hyaluronic acid that intensely hydrates the skin, helping to plump it from the inside out.

Longer term wrinkle resistance is delivered through Human Tripeptide-1 that activates the skin’s internal repair system, helping to boost collagen synthesis and strengthen the underlying dermal matrix. Collagen production and protection is further enhanced through specialised bioactive peptides that are encapsulated by 24 carat gold particles, to support deeper and more effective action.

Read more Show less



relaxation of muscles that cause wrinkles after 4 hours*


relaxation of muscles that cause wrinkles after 24 hours*


relaxation of muscles that cause wrinkles after 48 hours*

*Independent 3D in vitro testing (2024)

"It’s not often I’m genuinely shocked by a beauty product, but the results I saw might just be enough to end my journey with retinol (and invasive treatments)"

Supernatural Vitale Elixir Refill

How to Refill and Routine

Directly after cleansing apply 1-2 pumps of the Elixir generously to the face. To use as a targeted treatment, you can apply directly to areas of concern, however preventative action is most effective when the Elixir is applied to the full face. Use in the morning and night for optimal results. If you are also using the Supernatural Blemish Serum in your routine, we advise using this first, then apply your Supernatural Vitale Elixir before any other serums or crèmes.

Watch Video

Emma's Tips

Clinical Testing and Ingredients

Emma Lewisham's Physiology Synchrony Unlock Method™ is our proprietary skin-first formulating philosophy, which blends up to 25 scientific ingredients that are selected for their proven effect on the skin. The true breakthrough happens when these ingredients work in symphony across multiple skin pathways to unlock transformational results.

Our formulations are fundamentally different. Uniquely developed by scientists and physiologists with over 100 years combined experience, our formulas are engineered with up to 25 meticulously chosen ingredients that are individually efficacious, but in combination amplify each other to provide three-dimnesional, next generation results.

The most powerful way to interact with the skin is naturally, therefore we only use natural ingredients, harnessing both bio-identical ingredients found within the skin as well as the specialised, scientifically proven natural plant extracts. These bio-active ingredients work in harmony with the skin to trigger powerful cellular responses that deliver unparalleled results.

While our ingredients are natural, naturally derived and nature identical, we recommend doing a patch test or consulting your medical practitioner before using any new skincare product, particularly if you have sensitive skin or allergies.

Clinical Testing Results Arrow

The results of this formulation are validated at the highest level with unparallelled independent scientific grade testing at both an in vitro (laboratory) and in vivo (clinical) level.

Pioneering independent 3D in vitro (2024) testing performed by a specialist French laboratory using a Reconstructed Human Epidermis, found that the Supernatural Vitale Elixir relaxed the muscle contractions that cause wrinkles by up to:

  • 62% after 4 hours
  • 91% after 24 hours
  • 96% after 48 hours

  • An independent 12-week consumer trial using an OBSERV Skin Analyser (2024) and investigating Supernatural Vitale Elixir’s impact on wrinkle reduction and hydration found that it:
  • Reduced the depth and length of facial wrinkles by at least 45%.
  • Improved skin plumpness and hydration by up to 75%.
  • Improved the skin’s structural integrity and cellular turnover.

  • Independent in vivo testing over 14 weeks (2023) investigating the impact on fine lines and wrinkles found:
  • 90% of users felt moderately or extremely satisfied about skin’s smoothness after product’s use.
  • 73% of the users felt moderately or extremely satisfied about skin’s firmness after product’s use.
  • 60% of the users saw improvement to the appearance of their skin over and above reduction of wrinkles.

  • Independent in vivo testing over 14 weeks (2023) investigating Supernatural Vitale Elixir’s impact on hydration found that it decreases the skin’s transepidermal water loss to maintain superior hydration.

    Ingredients Arrow


    • Neuroinhibitor technology: Contains a Topical Relaxant Complex with Acetyl Hexapeptide-8, Leucojum aestivum bulb extract, and Acmella oleracea extract, that reduce expression lines to help smooth the look of wrinkles.

    • Peptides with advanced lipid delivery system: Contains two peptides with advanced Lipid Delivery System. The Elixir uses a plant-sourced derivation of Human Tripeptide-1, isolated from wild-picked seeds of cedar trees to work with our skin’s reparative system to strengthen its underlying structure, so it works from the inside-out. This peptide, forms part of a two-part messenger system alongside a bioactive collagen-boosting peptide, palmitoyl pentapeptide-4, to increase the skin’s collagen production. This peptide is protected by gold particles that reduce its degradation by the skin’s enzymes, for superior efficacy.

    • Hydrafilling technology: Instant filling effect to smooth the skin with 72 hour hydration technology. Contains new moisture enhancing technology, harnessing hydration heroes Saccharide Isomerate and Acetylated Hyaluronic Acid – a modified Hyaluronic Acid that can penetrate more deeply and demonstrates impressive resistance to degradation by the skin’s enzymes. This pairing together provide instant hydrafilling and plumping for a smooth and plump appearance.

    Ingredients List

    Aloe barbadensis leaf extract • Water / aqua / eau • Helianthus annuus (Sunflower) seed oil • Glycerin • Propanediol • Coco-caprylate • Saccharide isomerate • Glyceryl stearate citrate • Cetearyl alcohol • Shea butter ethyl esters • Benzyl alcohol • Parfum (fragrance) • Tocopherol • Tocopheryl acetate • Acmella oleracea extract • Colloidal gold • Glyceryl caprylate • Lecithin • Palmitoyl pentapeptide-4 • Acetyl hexapeptide-8 • Sodium acetylated hyaluronate • Acanthopanax senticosus (Eleuthero) root extract • Leucojum aestivum bulb extract • Pullulan • Hydrolyzed pinus sibirica seedcake extract • Sodium benzoate • Pentylene glycol • Citric acid • Caprylyl glycol • 1,2- Hexanediol • Sodium hydroxide • Mica • Dehydroacetic acid • Tin oxide • CI 77492 (Iron oxides) • CI 77891 (Titanium dioxide) • Silica • Xanthan gum • Sclerotium gum • Menthane carboxamide ethylpyridine • Menthyl PCA • Lactamide MEA • Sodium citrate • Alpha-isomethyl ionone • Coumarin • Limonene • Linalool

    White Paper Arrow

    Read our white paper for comprehensive information about this specific product formulation.

    Read the white paper

    Sustainability and Refills

    Through our global circularity programme, ‘Beauty Circle’, we take back all of our used packaging to be refilled or recycled.

    Repurchasing Supernatural Vitale Elixir? By choosing to buy this refill instead of a new bottle, you'll reduce your carbon footprint.

    Read our detailed packaging information.

    Purchase the Refill

    Customer Reviews

    Based on 5 reviews
    Less packaging waste

    Oh I love Emma Lewisham skin care. She really does have a beautiful product and the fact she has thought about sustainability is a game changer. You can buy refills for all her products which reduces packaging waste and you can return the empty plastic packing to source too. Helps that the products work a dream too. Love it!

    I can't believe how much it has worked!!!

    I bought this yesterday mid morning, put it on at lunch time, and bed time and again this morning. it's 7:50am (so not even 24hrs later) and I can't believe how much it has worked!!! And so quickly. Highhhly recommend!

    So glad I purchased!

    I have been using this product for a number of weeks and absolutely had to stock up after finishing it. I cannot be without this product! From it's wonderful hydration to it's lovely scent, I am sold! Wrinkles reduced and skin plumper. I will be back time and time again!

    Glowing skin & no waste

    I love this serum and I am so happy that there is a refillable option. Its great to have a brand that not only create great products but is also looking after the world at the same time.

    It actually works

    I have been using this product for two months and have noticed dramatic changes to the fine lines and wrinkles all over my face, especially around my eyes. Worth every dollar.